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Refractoriness to platelet transfusion in the presence of anti-HLA antibodies—reassessing the alloantibody hypothesis

   
@article{AOB4909,
	author = {James C. Zimring and Christian Fink},
	title = {Refractoriness to platelet transfusion in the presence of anti-HLA antibodies—reassessing the alloantibody hypothesis},
	journal = {Annals of Blood},
	volume = {4},
	number = {0},
	year = {2019},
	keywords = {},
	abstract = {Since platelet products first became routinely available in the 1970s, platelet transfusions have been a mainstay of the treatment of thrombocytopenic patients, decreasing the frequency and severity of bleeding sequelae (1). While the overall clinical goal is to decrease bleeding, the success of a platelet transfusion is often determined by an increase in platelet count post-transfusion [often reported as corrected count increment (CCI)] (2). The CCI may range from a substantial increase in platelet count to no effect at all; in some cases, a decrease in CCI can even be observed post-transfusion.},
	issn = {2521-361X},	url = {https://aob.amegroups.org/article/view/4909}
}